Guanylate cyclase C agonists: emerging gastrointestinal therapies and actions

Gastroenterology. 2015 Mar;148(3):483-7. doi: 10.1053/j.gastro.2015.01.003. Epub 2015 Jan 7.

Author

Michael Camilleri¹

Affiliation

¹ Clinical Enteric Neuroscience Translational and Epidemiological Research (C. E. N. T. E. R.), College of Medicine, Mayo Clinic, Rochester, Minnesota.

PMID: 25576859
DOI: 10.1053/j.gastro.2015.01.003

No abstract available

MeSH terms

Apoptosis / drug effects
Chlorides
Colon / drug effects
Constipation / drug therapy*
Constipation / etiology
Gastrointestinal Agents / pharmacology
Gastrointestinal Agents / therapeutic use*
Humans
Intestinal Mucosa / drug effects
Irritable Bowel Syndrome / complications
Irritable Bowel Syndrome / drug therapy*
Natriuretic Peptides / pharmacology
Natriuretic Peptides / therapeutic use*
Peptides / pharmacology
Peptides / therapeutic use*
Receptors, Atrial Natriuretic Factor / agonists*

Substances

Chlorides
Gastrointestinal Agents
Natriuretic Peptides
Peptides
plecanatide
Receptors, Atrial Natriuretic Factor
atrial natriuretic factor receptor C
linaclotide