Diagnostic value of core needle biopsy and fine-needle aspiration in salivary gland lesions

Head Neck. 2016 Apr:38 Suppl 1:E346-52. doi: 10.1002/hed.23999. Epub 2015 Jul 6.

Abstract

Background: Core needle biopsy (CNB) has gained acceptance as a minimally invasive procedure in the head and neck. Nevertheless, many concerns arise regarding the value and safety of this method in the assessment of salivary gland lesions.

Methods: This prospective study comprises 111 patients with a salivary gland lesion. The results of ultrasound-guided CNB were compared with those of fine-needle aspiration (FNA) in the 103 histologically verified cases.

Results: CNB achieved a higher accuracy than FNA in identifying true neoplasms (98% vs 91%) and detecting malignancy (99% vs 87%), and was also superior to FNA providing a specific diagnosis (93% vs 74%). In both methods, no complications, such as bleeding, infection, nerve injury, or tumor-cell seeding, occurred.

Conclusion: CNB is a simple, safe, and highly accurate procedure, which should be considered as an additional diagnostic tool in the assessment of salivary gland lesions. © 2015 Wiley Periodicals, Inc. Head Neck 38: E346-E352, 2016.

Keywords: core needle biopsy; fine-needle aspiration; salivary gland; tumor-cell seeding; ultrasound.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Biopsy, Fine-Needle*
  • Biopsy, Large-Core Needle*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Prospective Studies
  • Salivary Glands / pathology*
  • Sensitivity and Specificity
  • Young Adult