Analytical method for the quantification of 2',3'-didehydro-3'-deoxythymidine, a new anti-human immunodeficiency virus (HIV) agent, by high-performance liquid chromatography (HPLC) and ultraviolet (UV) detection in rat and monkey plasma

Pharm Res. 1989 Oct;6(10):895-9. doi: 10.1023/a:1015972824915.

Authors

S Kaul¹, K A Dandekar, K A Pittman

Affiliation

¹ Metabolism and Pharmacokinetics, Pharmaceutical Research, Bristol-Myers Company, Syracuse, New York 13221.

PMID: 2558374
DOI: 10.1023/a:1015972824915

No abstract available

MeSH terms

Acquired Immunodeficiency Syndrome / drug therapy*
Animals
Antiviral Agents / blood*
Chromatography, High Pressure Liquid
Dideoxynucleosides / blood*
Macaca fascicularis
Rats
Species Specificity
Spectrophotometry, Ultraviolet
Stavudine

Substances

Antiviral Agents
Dideoxynucleosides
Stavudine