Herpes Gestationis after Ovodonation: Is Placenta the only Target of the Immune Reaction?

J Clin Diagn Res. 2014 Nov;8(11):OD01-2. doi: 10.7860/JCDR/2014/8727.5103. Epub 2014 Nov 20.

Abstract

Herpes Gestationis (HG) is an autoimmune disorder that rarely complicates pregnancy. Its pathogenesis has not been clarified yet, as it derives from a complex interplay between immunologic, genetic, and hormonal factors. We present a case of HG occurring in a surrogate mother whose pregnancy was achieved via egg donation and in vitro fertilisation (IVF). The disease appeared at 26 weeks and 6 days of gestation and subsequently worsened despite the administration of oral and topic corticosteroids. A healthy baby was delivered at 35 weeks and 2 days of gestation by elective cesarean section and the clinical manifestations resolved in the postpartum period.

Keywords: Autoimmunity; Dermatoses of pregnancy; Herpes gestationis; Ovodonation; Prurigo gestationis.

Publication types

  • Case Reports