Refined mapping of the three DNA repair genes, ERCC1, ERCC2, and XRCC1, on human chromosome 19

Cytogenet Cell Genet. 1989;52(1-2):11-4. doi: 10.1159/000132829.


Three DNA repair genes, ERCC1, ERCC2, and XRCC1, have been regionally mapped on human chromosome 19. ERCC2 and XRCC1 have been assigned to bands q13.2----q13.3 by in situ hybridization using fluorescently-labeled cosmid probes. ERCC1 and ERCC2 have been found to be separated by less than 250 kb by large fragment restriction enzyme site mapping.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Blotting, Southern
  • Chromosome Mapping
  • Chromosomes, Human, Pair 19*
  • DNA
  • DNA Probes
  • DNA Repair / genetics*
  • DNA Restriction Enzymes
  • Electrophoresis, Agar Gel
  • Female
  • Genetic Linkage
  • Humans
  • Nucleic Acid Hybridization


  • DNA Probes
  • DNA
  • DNA Restriction Enzymes