Host CD8α+ dendritic cells may be a key factor for separating graft-versus-host disease from graft-versus-leukemia

Biol Blood Marrow Transplant. 2015 Apr;21(4):775-6. doi: 10.1016/j.bbmt.2015.01.005. Epub 2015 Jan 13.

Authors

Tomomi Toubai¹, Nathan Mathewson², Katherine Oravecz-Wilson², Pavan Reddy²

Affiliations

¹ Blood and Marrow Transplantation Program, Division of Hematology and Oncology, Department of Internal Medicine, University of Michigan Comprehensive Cancer Center, Ann Arbor, Michigan. Electronic address: tomomit@med.umich.edu.
² Blood and Marrow Transplantation Program, Division of Hematology and Oncology, Department of Internal Medicine, University of Michigan Comprehensive Cancer Center, Ann Arbor, Michigan.

PMID: 25591846
DOI: 10.1016/j.bbmt.2015.01.005

No abstract available

Publication types

Letter
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

MeSH terms

Allografts
Animals
Bone Marrow Transplantation*
CD8 Antigens / genetics
CD8 Antigens / immunology*
Dendritic Cells / immunology*
Dendritic Cells / pathology
Disease Models, Animal
Graft vs Host Disease / genetics
Graft vs Host Disease / immunology*
Graft vs Host Disease / pathology
Graft vs Leukemia Effect / genetics
Graft vs Leukemia Effect / immunology*
Mice
Mice, Knockout

Substances

CD8 Antigens
CD8 antigen, alpha chain

Grants and funding