Cardiac resynchronization therapy: history, present status, and future directions

Ochsner J. 2014 Winter;14(4):596-607.


Background: Cardiac resynchronization therapy (CRT) is one of the most exciting recent advancements in heart failure (HF) treatment.

Methods: This review surveys the available literature regarding the effectiveness of CRT in treating patients with HF.

Results: By targeting ventricular dyssynchrony, CRT attempts to give the failing heart a mechanical advantage that can substantially improve both symptoms and mortality.

Conclusion: CRT results in short-term and long-term improvement in cardiac structure and function, often leading to enhanced quality of life and, for some patients, enhanced survival.

Keywords: Cardiac electrophysiology; cardiac resynchronization therapy; heart failure; myocardial infarction.

Publication types

  • Review