Accelerometer-monitored sedentary behavior and observed physical function loss

Am J Public Health. 2015 Mar;105(3):560-6. doi: 10.2105/AJPH.2014.302270. Epub 2015 Jan 20.


Objectives: We examined whether objectively measured sedentary behavior is related to subsequent functional loss among community-dwelling adults with or at high risk for knee osteoarthritis.

Methods: We analyzed longitudinal data (2008-2012) from 1659 Osteoarthritis Initiative participants aged 49 to 83 years in 4 cities. Baseline sedentary time was assessed by accelerometer monitoring. Functional loss (gait speed and chair stand testing) was regressed on baseline sedentary time and covariates (baseline function; socioeconomics [age, gender, race/ethnicity, income, education], health factors [obesity, depression, comorbidities, knee symptoms, knee osteoarthritis severity, prior knee injury, other lower extremity pain, smoking], and moderate-to-vigorous activity).

Results: This cohort spent almost two thirds of their waking hours (average=9.8 h) in sedentary behaviors. Sedentary time was significantly positively associated with subsequent functional loss in both gait speed (-1.66 ft/min decrease per 10% increment sedentary percentage waking hours) and chair stand rate (-0.75 repetitions/min decrease), controlling for covariates.

Conclusions: Being less sedentary was related to less future decline in function, independent of time spent in moderate-to-vigorous activity. Both limiting sedentary activities and promoting physical activity in adults with knee osteoarthritis may be important in maintaining function.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Accelerometry / instrumentation
  • Accelerometry / methods
  • Aged
  • Aged, 80 and over
  • Body Mass Index
  • Female
  • Gait / physiology*
  • Humans
  • Longitudinal Studies
  • Male
  • Middle Aged
  • Monitoring, Physiologic / instrumentation
  • Monitoring, Physiologic / methods
  • Motor Activity*
  • Osteoarthritis, Knee / etiology*
  • Osteoarthritis, Knee / prevention & control
  • Protective Factors
  • Risk Factors
  • Sedentary Behavior*
  • Time Factors
  • United States