A systems approach to drug discovery in Alzheimer's disease

Neurotherapeutics. 2015 Jan;12(1):126-31. doi: 10.1007/s13311-014-0335-5.


In the articles included in this volume, one feels a strong frustration among the writers with the slow course of therapeutics development for Alzheimer's disease and with the clinical failure of targeted therapeutic agents despite substantial progress in our understanding of the biology and biochemistry of the disease.

Publication types

  • Review

MeSH terms

  • Alzheimer Disease / drug therapy*
  • Animals
  • Drug Discovery / methods*
  • Humans
  • Systems Analysis*