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Review
. 1989;29(6):639-51.

[Signal Transmission Using Second Messengers]

[Article in French]
Affiliations
  • PMID: 2560919
Review

[Signal Transmission Using Second Messengers]

[Article in French]
C Pfister. Reprod Nutr Dev. .

Abstract

Intercellular communication needs signal molecules (hormones, neurotransmitters, growth factors) emitted by a cell and recognized by targets. A widespread mechanism of cellular action of these molecules involves a membrane receptor, a GTP-dependent coupling protein, an effector which modulates the intracellular concentration of a second messenger (cAMP, cGMP, inositol triphosphate, Ca++), and a target for final effect of this second messenger (kinases, channel). Hormonal systems and visual processes in vertebrates rod outer segments are the best known examples of this mechanism; they are taken here to illustrate the state of knowledge of the interactions between the actors of the transductional enzymatic cascades.

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