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, 11 (2), 321-6

Single Anastomosis or Mini-Gastric Bypass: Long-Term Results and Quality of Life After a 5-year Follow-Up


Single Anastomosis or Mini-Gastric Bypass: Long-Term Results and Quality of Life After a 5-year Follow-Up

Matthieu Bruzzi et al. Surg Obes Relat Dis.


Background: Laparoscopic mini-gastric bypass (LMGB) is an alternative to the laparoscopic Roux-en-Y gastric bypass (LRYGB), which is considered to be the gold standard in the treatment of morbid obesity.

Objectives: Present 5-year results of 175 patients who had undergone a LMGB between October 2006 and October 2008.

Setting: University public hospital, France.

Methods: Complete follow-up was available in 126 of 175 patients (72%) who had LMGB. Mortality, morbidity, weight loss, co-morbidities, and quality of life were assessed. Weight loss was determined as a change in body mass index (BMI) and percent excess BMI loss (%EBMIL). Quality of life in the treatment group was analyzed using the Gastrointestinal Quality of Life Index (GIQLI) and was compared with a retrospectively case matched preoperative control group.

Results: There were no deaths. Thirteen patients (10.3%) developed major complications. Marginal ulcers occurred in 4% of patients. Incapacitating biliary reflux developed in 2 (1.6%) who required conversion into RYGB. Gastric pouch dilation occurred in 4 patients (3.2%) and inadequate weight loss with severe malnutrition in 2 (1.6%). At 5 years, mean BMI was 31±6 kg/m(2) and mean %EBMIL was 71.5%±26.5%. Postoperative GIQLI score of the treatment group was significantly higher than preoperative score of the control group (110.3±17.4 versus 92.5±15.9, P<.001). Social, psychological, and physical functions were increased significantly. No significant differences were found in gastroesophageal reflux or diarrhea symptoms between the 2 groups. Long-term follow-up showed an improvement in all co-morbidities.

Conclusions: At 5 years, LMGB was safe, effective, and provided interesting quality of life results.

Keywords: BMI; Mini-gastric bypass; Morbid obesity; Quality of life; Weight loss.

Comment in

  • Has mini gastric bypass come of age?
    Bindal V, Sudan R. Bindal V, et al. Surg Obes Relat Dis. 2015 Mar-Apr;11(2):326-7. doi: 10.1016/j.soard.2014.10.001. Epub 2014 Oct 7. Surg Obes Relat Dis. 2015. PMID: 25620434 No abstract available.

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