Quadrimodal distribution of death after trauma suggests that critical injury is a potentially terminal disease

J Crit Care. 2015 Jun;30(3):656.e1-7. doi: 10.1016/j.jcrc.2015.01.003. Epub 2015 Jan 8.

Abstract

Background: Patterns of death after trauma are changing due to advances in critical care. We examined mortality in critically injured patients who survived index hospitalization.

Methods: Retrospective analysis of adults admitted to a Level-1 trauma center (1/1/2000-12/31/2010) with critical injury was conducted comparing patient characteristics, injury, and resource utilization between those who died during follow-up and survivors.

Results: Of 1,695 critically injured patients, 1,135 (67.0%) were discharged alive. As of 5/1/2012, 977/1,135 (86.0%) remained alive; 75/158 (47.5%) patients who died during follow-up, died in the first year. Patients who died had longer hospital stays (24 vs. 17 days) and ICU LOS (17 vs. 8 days), were more likely to undergo tracheostomies (36% vs. 16%) and gastrostomies (39% vs. 16%) and to be discharged to rehabilitation (76% vs. 63%) or skilled nursing (13% vs. 5.8%) facilities than survivors. In multivariable models, male sex, older age, and longer ICU LOS predicted mortality. Patients with ICU LOS >16 days had 1.66 odds of 1-year mortality vs. those with shorter ICU stays.

Conclusions: ICU LOS during index hospitalization is associated with post-discharge mortality. Patients with prolonged ICU stays after surviving critical injury may benefit from detailed discussions about goals of care after discharge.

Keywords: Critical injury; Goals of care; Injury mortality; Trauma mortality.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Adult
  • Age Factors
  • Aged
  • Critical Care
  • Female
  • Hospitalization
  • Humans
  • Intensive Care Units
  • Length of Stay / statistics & numerical data*
  • Male
  • Middle Aged
  • Multivariate Analysis
  • Patient Discharge
  • Rehabilitation Centers / statistics & numerical data*
  • Retrospective Studies
  • Risk Factors
  • Sex Factors
  • Skilled Nursing Facilities / statistics & numerical data*
  • Tracheostomy / statistics & numerical data*
  • Trauma Centers
  • Wounds and Injuries / mortality*