A case of subcutaneous seeding of hepatocellular carcinoma after fine needle aspiration biopsy

Korean J Intern Med. 1989 Jan;4(1):96-100. doi: 10.3904/kjim.1989.4.1.96.


Cancer spread along the needle track following fine needle aspiration biopsy is said to be a rare complication. The authors report a case of subcutaneous implantation of hepatocellular carcinoma following ultrasono-guided fine needle aspiration biopsy. The patient, a 67-year-old Korean male was found to have a large hepatocellular carcinoma diagnosed by fine needle aspiration biopsy. Four months later, the patient felt two subcutaneous growing lumps at the previous aspiration site. The authors confirmed them histologically 11 months after aspiration.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Biopsy, Needle / adverse effects*
  • Carcinoma, Hepatocellular / pathology*
  • Carcinoma, Hepatocellular / secondary
  • Humans
  • Liver Neoplasms / pathology*
  • Male
  • Neoplasm Seeding*
  • Skin Neoplasms / pathology
  • Skin Neoplasms / secondary*