Study of cutaneous leishmaniasis in the State of Campeche (Yucatan Peninsula), Mexico, over a period of two years

Salud Publica Mex. 2015 Jan-Feb;57(1):58-65. doi: 10.21149/spm.v57i1.7403.

Abstract

Objective: To study cutaneous leishmaniasis (CL), in the Calakmul municipality of the Campeche State, during two years.

Materials and methods: Individuals with skin lesions were evaluated. Aspirates taken from the lesions were cultured, PCR was performed to diagnose the Leishmania species.

Results: The culture detected 42% of the samples. PCR diagnosed CL in 76% of the samples; of those 38% were from children and 62% from adults. 89% of the patients were infected with L. mexicana; 14.4% with Mexican strains of L. mexicana; 7% with L. braziliensis; 3.6% with L. mexicana and L. braziliensis. The most affected villages with CL were Dos Lagunas Sur with 12.3%, La Mancolona with 6.5% and La Guadalupe with 2.2% of prevalence, respectively. After the treatment with Glucantime, 96% of the patients were healed.

Conclusion: CL is an important public health concern in Calakmul, and the parasite causing it belongs to Leishmania mexicana and Leishmania braziliensis complexes.

MeSH terms

  • Adult
  • Animals
  • Antiprotozoal Agents / therapeutic use
  • Child
  • DNA, Protozoan / analysis
  • Disease Reservoirs
  • Female
  • Geography, Medical
  • Humans
  • Leishmania braziliensis / isolation & purification
  • Leishmania mexicana / isolation & purification
  • Leishmaniasis, Cutaneous / epidemiology*
  • Leishmaniasis, Cutaneous / parasitology
  • Male
  • Meglumine / therapeutic use
  • Meglumine Antimoniate
  • Mexico / epidemiology
  • Organometallic Compounds / therapeutic use
  • Prevalence
  • Remission Induction
  • Rodentia / parasitology

Substances

  • Antiprotozoal Agents
  • DNA, Protozoan
  • Organometallic Compounds
  • Meglumine
  • Meglumine Antimoniate