Morbidity of very low birthweight infants at corrected age of two years in a geographically defined population. Report from Project on Preterm and Small for gestational age infants in The Netherlands

Lancet. 1989 Feb 4;1(8632):253-5. doi: 10.1016/s0140-6736(89)91265-8.


In a nationwide prospective survey on very preterm and very-low-birthweight infants in the Netherlands, a neurodevelopmental assessment was made at the corrected age of two years in a virtually complete population. The study achieved a 97.4% follow-up rate. A major handicap was found in 59 children and a minor handicap in 111 children (4.4% and 8.3% of liveborn infants, respectively). Unlike mortality, handicap was apparently unrelated to gestational age or birthweight.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Age Factors
  • Cause of Death
  • Congenital Abnormalities / epidemiology
  • Female
  • Follow-Up Studies
  • Humans
  • Infant Mortality*
  • Infant, Low Birth Weight*
  • Infant, Newborn
  • Infant, Premature*
  • Infant, Small for Gestational Age
  • Intellectual Disability / epidemiology
  • Male
  • Netherlands
  • Neurologic Examination
  • Prospective Studies