Acute psychosis presenting in a patient with systemic lupus erythematosus: Questions and Answers

Sheena Sharma; Melissa A Lerman; Mark P Fitzgerald; Rebecca L Ruebner

doi:10.1007/s00467-015-3052-3

Acute psychosis presenting in a patient with systemic lupus erythematosus: Questions and Answers

Pediatr Nephrol. 2016 Feb;31(2):227-31. doi: 10.1007/s00467-015-3052-3. Epub 2015 Jan 30.

Authors

Sheena Sharma¹, Melissa A Lerman², Mark P Fitzgerald³, Rebecca L Ruebner⁴

Affiliations

¹ Division of Nephrology, The Children's Hospital of Philadelphia, 34th Street and Civic Center Boulevard, Philadelphia, PA, 19104, USA. SharmaS2@email.chop.edu.
² Division of Rheumatology, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.
³ Division of Neurology, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.
⁴ Division of Nephrology, The Children's Hospital of Philadelphia, 34th Street and Civic Center Boulevard, Philadelphia, PA, 19104, USA.

PMID: 25634549
DOI: 10.1007/s00467-015-3052-3

Abstract

A 17-year-old girl recently diagnosed with systemic lupus erythematosus (SLE) presented to the Emergency Room with acute onset of psychosis. A variety of potential etiologies, including those related to SLE, to the treatment of her SLE, or to another psychiatric condition, are discussed. In addition, the work-up and management decisions for this patient are reviewed in detail.

Keywords: Acute psychosis; Corticosteroids; Systemic lupus erythematosus.

Publication types

Case Reports
Research Support, Non-U.S. Gov't

MeSH terms

Adolescent
Diagnosis, Differential
Female
Glucocorticoids / adverse effects*
Humans
Lupus Erythematosus, Systemic / diagnosis
Lupus Erythematosus, Systemic / drug therapy*
Lupus Nephritis / diagnosis
Lupus Nephritis / drug therapy*
Prednisolone / adverse effects*
Psychoses, Substance-Induced / diagnosis
Psychoses, Substance-Induced / etiology*

Substances

Glucocorticoids
Prednisolone