Central nervous system infection with non-tuberculous mycobacteria: a report of that infection in two patients with AIDS

Drug Discov Ther. 2014 Dec;8(6):276-9. doi: 10.5582/ddt.2014.01047.

Abstract

Meningitis caused by non-tuberculous mycobacteria (NTM) has a low incidence and is a rare form of NTM infection. In an increasing number of cases, however, disseminated mycobacterial infection is noted in acquired immune deficiency syndrome (AIDS). Described here are two patients with AIDS who were infected with NTM. Both patients eventually died, but one did receive anti-NTM treatment. Non-tuberculous mycobacterial meningitis must be suspected in patients with AIDS who present with prolonged fever and brain symptoms, and anti-NTM drugs should be promptly administered if necessary.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acquired Immunodeficiency Syndrome / complications*
  • Adult
  • Anti-Bacterial Agents / therapeutic use
  • Central Nervous System Infections / cerebrospinal fluid
  • Central Nervous System Infections / complications*
  • Central Nervous System Infections / drug therapy*
  • Fatal Outcome
  • Humans
  • Male
  • Meningitis, Bacterial / complications
  • Meningitis, Bacterial / drug therapy
  • Middle Aged
  • Mycobacterium Infections, Nontuberculous / cerebrospinal fluid
  • Mycobacterium Infections, Nontuberculous / complications*
  • Mycobacterium Infections, Nontuberculous / drug therapy*
  • Nontuberculous Mycobacteria*

Substances

  • Anti-Bacterial Agents