Photothermal theragnosis synergistic therapy based on bimetal sulphide nanocrystals rather than nanocomposites

Adv Mater. 2015 Feb 25;27(8):1339-45. doi: 10.1002/adma.201404257. Epub 2015 Jan 12.

Abstract

A new generation of photothermal theranostic agents is developed based on Cu3BiS3 nanocrystals. A computed tomography imaging response and photothermal effect, as well as near-infrared fluorescence emission, can be simultaneously achieved through Cu3BiS3 nanocrystals rather than frequently used nanocomposites. These results provide some insight into the synergistic effect from bimetal sulphide semiconductor compounds for photothermal theragnosis therapy.

Keywords: Cu3BiS3 nanocrystals; computed tomography (CT) imaging; near-infrared response; photothermal theragnosis therapy.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Bismuth / chemistry*
  • Cell Line, Tumor
  • Copper / chemistry*
  • Mice
  • Nanoparticles / chemistry*
  • Nanoparticles / therapeutic use*
  • Phototherapy / methods*
  • Sarcoma, Ewing / diagnosis
  • Sarcoma, Ewing / pathology
  • Sarcoma, Ewing / therapy
  • Sulfides / chemistry*
  • Theranostic Nanomedicine / methods*
  • Tomography, X-Ray Computed

Substances

  • Sulfides
  • Copper
  • Bismuth