Instability of the bovine MOR-2AB (mitochondrial malate: NAD oxidoreductase) heterodimeric molecule of heterozygous subjects after isoelectric focusing

Biochem Genet. 1978 Feb;16(1-2):121-6. doi: 10.1007/BF00484388.

Abstract

The heterodimeric molecule which is characteristic of animals heterozygous for the MOR-2 polymorphism and which is readily seen on enzymograms after electrophoresis is reported to be absent from zymograms performed after isoelectric focusing. A possible explanation is presented based on monomer--dimer equilibrium at pH 8.0--8.5.

MeSH terms

  • Animals
  • Cattle
  • Electrophoresis, Polyacrylamide Gel
  • Heterozygote
  • Hydrogen-Ion Concentration
  • Isoelectric Focusing*
  • Malate Dehydrogenase / genetics
  • Malate Dehydrogenase / isolation & purification
  • Malate Dehydrogenase / metabolism*
  • Muscles / enzymology
  • Polymorphism, Genetic*

Substances

  • Malate Dehydrogenase