Dysbiosis of the gut microbiota in disease

Microb Ecol Health Dis. 2015 Feb 2:26:26191. doi: 10.3402/mehd.v26.26191. eCollection 2015.


There is growing evidence that dysbiosis of the gut microbiota is associated with the pathogenesis of both intestinal and extra-intestinal disorders. Intestinal disorders include inflammatory bowel disease, irritable bowel syndrome (IBS), and coeliac disease, while extra-intestinal disorders include allergy, asthma, metabolic syndrome, cardiovascular disease, and obesity.

Keywords: Microbiome; colonic metabolome; gut health; gut–brain–axis; inflammation; short-chain fatty acids.