Recent advances in magnetic nanoparticle-based multi-modal imaging

Chem Soc Rev. 2015 Jul 21;44(14):4501-16. doi: 10.1039/c4cs00345d.


Magnetic nanoparticles have been extensively explored as a versatile platform for magnetic resonance imaging (MRI) contrast agents due to their strong contrast enhancement effects together with the platform capability for multiple imaging modalities. In this tutorial review, we focus on recent progress in the use of magnetic nanoparticles for MRI contrast agents and multi-mode imaging agents such as T1-T2 MRI, MRI-optical, and MRI-radioisotopes. This review also highlights emerging magnetic imaging techniques such as magnetic particle imaging (MPI), magneto-motive ultrasound imaging (MMUS), and magneto-photoacoustic imaging (MPA).

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Cell Line, Tumor
  • Fluorescent Dyes
  • Humans
  • Magnetite Nanoparticles*
  • Mice
  • Multimodal Imaging / methods*
  • Multimodal Imaging / trends*
  • Radioactive Tracers


  • Fluorescent Dyes
  • Magnetite Nanoparticles
  • Radioactive Tracers