The goal of surgical treatment for gastrointestinal stromal tumor (GIST) is the complete resection of the tumor. A 62-year-old male had a clearly distinguishable mass having a smooth surface at the right side of the lower esophagus by computed tomography. Thoracoscopic resection of the tumor was performed. Immunohistochemical analysis showed that the tumor was positive for c-KIT and CD34 without mitosis, and diagnosed to be a low-risk GIST. At 6 years after surgery, the patient survived without recurrence. This study described the long-term surviving patient without the recurrence of tumor after the thoracoscopic resection of an esophageal GIST.
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