CTX-M-15-non-ST131 Escherichia coli isolates are mainly responsible of faecal carriage with ESBL-producing Enterobacteriaceae in travellers, immigrants and those visiting friends and relatives

Clin Microbiol Infect. 2015 Mar;21(3):252.e1-4. doi: 10.1016/j.cmi.2014.09.021. Epub 2014 Oct 29.

Abstract

Prevalence of extended-spectrum β-lactamases (ESBL) and/or carbapenemase-producing Enterobacteriaceae (EPE and CPE) in stool samples from 75 travellers, 8 people visiting friends and relatives and 3 immigrants who had travelled or came from tropical or subtropical areas was determined. Thirty-one per cent (27/86) of the subjects were faecal carriers of EPE, and 37 EPE isolates were recovered (36 Escherichia coli, 1 Klebsiella pneumoniae). CTX-M-15 was the most prevalent enzyme (64.8%) mainly associated with E. coli belonging to phylogroup A and sequence type complex 10. Most of the ESBL-positive travellers (50%) had visited countries from Asia.

Keywords: CTX-M-15; VFR; faecal carriage; immigrants; non-ST131 Escherichia coli; travellers.

MeSH terms

  • Adolescent
  • Adult
  • Africa / epidemiology
  • Aged
  • Asia / epidemiology
  • Carrier State*
  • Emigrants and Immigrants*
  • Enterobacteriaceae / enzymology
  • Enterobacteriaceae Infections / epidemiology
  • Enterobacteriaceae Infections / microbiology
  • Escherichia coli / enzymology*
  • Escherichia coli / isolation & purification
  • Escherichia coli Infections / epidemiology*
  • Escherichia coli Infections / microbiology*
  • Feces / microbiology*
  • Female
  • Humans
  • Latin America / epidemiology
  • Male
  • Middle Aged
  • Travel*
  • Young Adult
  • beta-Lactamases / biosynthesis*
  • beta-Lactamases / genetics

Substances

  • beta-lactamase CTX-M-15
  • beta-Lactamases