Prospective and retrospective evaluation of the Cepheid Xpert® Flu/RSV XC assay for rapid detection of influenza A, influenza B, and respiratory syncytial virus

Diagn Microbiol Infect Dis. 2015 Apr;81(4):256-8. doi: 10.1016/j.diagmicrobio.2015.01.008. Epub 2015 Jan 24.

Abstract

A total of 281 clinical specimens (nasal swabs and nasopharyngeal aspirates) were tested with the Xpert® Flu/RSV XC. The results were compared to those obtained with the real-time retro transcriptase-polymerase chain reaction assays routinely used in our laboratory. The Xpert® Flu/RSV XC showed sensitivity/specificity of 97.8%/100% and 97.9%/100% for flu and respiratory syncytial virus, respectively.

Keywords: Diagnosis; Flu; Point-of-care; RT-PCR; Rapid Influenza Detection Test; Real-time PCR; Syncytial respiratory virus.

Publication types

  • Comparative Study
  • Evaluation Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Child
  • Child, Preschool
  • Female
  • Humans
  • Infant
  • Infant, Newborn
  • Influenza A virus / isolation & purification*
  • Influenza B virus / isolation & purification*
  • Influenza, Human / diagnosis*
  • Influenza, Human / virology
  • Male
  • Middle Aged
  • Molecular Diagnostic Techniques / methods*
  • Respiratory Syncytial Virus Infections / diagnosis
  • Respiratory Syncytial Virus Infections / virology
  • Respiratory Syncytial Viruses / isolation & purification*
  • Sensitivity and Specificity
  • Time Factors
  • Virology / methods*
  • Young Adult