Monoamine- and diamine oxidase activities in psoriasis

Acta Derm Venereol. 1989;69(3):264-5.

Abstract

Monoamine- and diamine oxidase activities were measured by a sensitive photometric assay in 25 psoriasis vulgaris patients. Results were compared with plasma histamine values determined fluorimetrically. Increased plasma histamine levels were associated with significantly lowered diamine--and type B monoamine oxidase activities in platelet-rich plasma of the psoriasis patients. Our data suggest that cofactor levels and/or inhibiting factors are responsible for the observed monoamine- and diamine oxidase activities.

MeSH terms

  • Adolescent
  • Adult
  • Amine Oxidase (Copper-Containing) / blood*
  • Histamine / blood
  • Humans
  • Monoamine Oxidase / blood*
  • Psoriasis / enzymology*

Substances

  • Histamine
  • Amine Oxidase (Copper-Containing)
  • Monoamine Oxidase