Abstract
Significant physiological changes are common among critically ill patients. This case-based review describes the consequences of these changes on the selection and dosing of medications.
MeSH terms
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Acute Kidney Injury / metabolism*
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Anti-Bacterial Agents / pharmacokinetics*
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Anti-Bacterial Agents / therapeutic use
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Anticoagulants / pharmacokinetics
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Anticoagulants / therapeutic use
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Critical Illness*
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Drug Interactions
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Fluid Shifts
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Fluid Therapy*
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Heparin, Low-Molecular-Weight / pharmacokinetics
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Heparin, Low-Molecular-Weight / therapeutic use
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Humans
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Hypotension / therapy*
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Male
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Middle Aged
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Pneumonia, Bacterial / drug therapy*
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Protein Binding
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Serum Albumin / metabolism*
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Venous Thromboembolism / prevention & control
Substances
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Anti-Bacterial Agents
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Anticoagulants
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Heparin, Low-Molecular-Weight
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Serum Albumin