Ultrasound-guided core biopsy

Lancet. 1989 Jun 17;1(8651):1369-71. doi: 10.1016/s0140-6736(89)92813-4.


Between February, 1986, and September, 1988, 404 biopsies have been done, under ultrasound guidance, with a cutting needle fired by a spring-loaded device. Sensitivity for a diagnosis of malignancy was 92.7%; overall accuracy was 94.1%; the predictive value of a positive result was 100% and the complication rate was low. An exact diagnosis could be made from histological examination of the specimen obtained from 98% of positive tumour biopsies. This technique is a simple and safe way to obtain specimens for accurate histological diagnosis.

MeSH terms

  • Adult
  • Biopsy, Needle / instrumentation*
  • Biopsy, Needle / methods
  • Evaluation Studies as Topic
  • False Negative Reactions
  • Histological Techniques / standards
  • Humans
  • Neoplasms / pathology*
  • Predictive Value of Tests
  • Ultrasonography*