S. epidermidis influence on host immunity: more than skin deep

Richard L Gallo

doi:10.1016/j.chom.2015.01.012

S. epidermidis influence on host immunity: more than skin deep

Cell Host Microbe. 2015 Feb 11;17(2):143-4. doi: 10.1016/j.chom.2015.01.012.

Author

Richard L Gallo¹

Affiliation

¹ Department of Dermatology, University of California San Diego, La Jolla, CA 92093, USA. Electronic address: rgallo@ucsd.edu.

Abstract

The mammalian immune system communicates with skin-resident microbes, and some of these microbes provide benefits to the host. In a recent paper in Nature, Naik et al. (2015) provide evidence that the murine epidermis permits S. epidermidis, a skin-specific bacterium, to shape the immune response.

Publication types

Comment

MeSH terms

Animals
CD8-Positive T-Lymphocytes / immunology*
Dendritic Cells / immunology*
Humans
Skin / immunology*
Skin / microbiology*
Symbiosis / immunology*

Grants and funding

R01 AR064781/AR/NIAMS NIH HHS/United States