Body fluid cell counts by automated methods

Linda M Sandhaus

doi:10.1016/j.cll.2014.10.003

Body fluid cell counts by automated methods

Clin Lab Med. 2015 Mar;35(1):93-103. doi: 10.1016/j.cll.2014.10.003. Epub 2014 Dec 4.

Author

Linda M Sandhaus¹

Affiliation

¹ Department of Pathology, University Hospitals Case Medical Center, 11100 Euclid Avenue, Cleveland, OH 44106-3205, USA. Electronic address: Linda.Sandhaus@UHhospitals.org.

PMID: 25676374
DOI: 10.1016/j.cll.2014.10.003

Abstract

Automated cell counting for body fluids is gradually replacing manual cell counting by hemocytometer. Automation offers potential benefits of improved accuracy, efficiency, and standardization. The addition of body fluid modes to some hematology analyzers adapts the technology and software to meet the particular requirements of body fluid analysis. However, the functional sensitivity for low cell counts currently limits applicability of automated methods to all types of body fluid. Microscopic review is indicated when malignancy is a diagnostic consideration.

Keywords: Automated body fluid analysis; Body fluids; Cell counting; Hematology analyzers.

Publication types

Review

MeSH terms

Automation
Body Fluids / cytology*
Cell Count / instrumentation
Cell Count / methods*
Humans
Quality Control
Reproducibility of Results
Validation Studies as Topic