Chromosomal localization of the human homeo box-containing genes, EN1 and EN2

Genomics. 1989 Feb;4(2):206-9. doi: 10.1016/0888-7543(89)90301-7.


The human homologs of the mouse homeo box-containing genes, En-1 and En-2, which show homology to the Drosophila engrailed gene, have been isolated. The human EN1 gene was mapped to chromosome 2 by analysis of mouse-human somatic cell hybrids. The human EN2 gene was localized to chromosome 7, 7q32-7qter, by analysis of rodent-human somatic cell hybrids and cell lines carrying portions of chromosome 7.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Blotting, Southern
  • Chromosome Mapping
  • Chromosomes, Human, Pair 2*
  • Chromosomes, Human, Pair 7*
  • Genes, Homeobox*
  • Humans
  • Hybrid Cells
  • Mice