Complete response to weekly carboplatin-docetaxel chemotherapy in a 91-year-old woman with anaplastic thyroid cancer

Haralabos Koussis; Carlo Alberto Giorgi; Elisabetta Di Liso; Maria Concetta Carlucci; Ambrogio Fassina; Gino Marioni; Pier Franco Conte

doi:10.1016/j.amjoto.2014.03.006

Complete response to weekly carboplatin-docetaxel chemotherapy in a 91-year-old woman with anaplastic thyroid cancer

Am J Otolaryngol. 2015 Mar-Apr;36(2):268-72. doi: 10.1016/j.amjoto.2014.03.006. Epub 2014 Mar 27.

Authors

Haralabos Koussis¹, Carlo Alberto Giorgi², Elisabetta Di Liso², Maria Concetta Carlucci³, Ambrogio Fassina⁴, Gino Marioni⁵, Pier Franco Conte²

Affiliations

¹ Division of Oncology 2, Istituto Oncologico Veneto (IOV-IRCCS), Padova, Italy. Electronic address: drbabis@libero.it.
² Division of Oncology 2, Istituto Oncologico Veneto (IOV-IRCCS), Padova, Italy.
³ Division of Psycho-Oncology, Istituto Oncologico Veneto (IOV-IRCCS), Padova, Italy.
⁴ Department of Medicine, Surgical Pathology and Cytopathology Unit, University of Padova, Padova, Italy.
⁵ Department of Neurosciences, Otolaryngology Section, Padova University, Padova, Italy.

PMID: 25681954
DOI: 10.1016/j.amjoto.2014.03.006

Abstract

Anaplastic thyroid cancer (ATC) is an unusual tumor with the worst prognosis among thyroid malignancies. Treatment of the patients diagnosed with ATC is not standardized and the feasible options include surgery, radiotherapy and chemotherapy. ATC cannot be regarded as a very chemo-sensitive tumor. Herein, we reported a case of a 91-year-old woman with complete response after induction chemotherapy (weekly carboplatin and docetaxel) that underwent subsequent radiotherapy.

Publication types

Case Reports
Review

MeSH terms

Aged, 80 and over
Antineoplastic Combined Chemotherapy Protocols / administration & dosage*
Antineoplastic Combined Chemotherapy Protocols / adverse effects
Biopsy, Fine-Needle
Carboplatin / administration & dosage
Docetaxel
Dose-Response Relationship, Drug
Drug Administration Schedule
Female
Follow-Up Studies
Humans
Immunohistochemistry
Positron-Emission Tomography / methods
Radiotherapy, Adjuvant
Rare Diseases
Remission Induction
Taxoids / administration & dosage
Thyroid Carcinoma, Anaplastic / diagnostic imaging
Thyroid Carcinoma, Anaplastic / drug therapy*
Thyroid Carcinoma, Anaplastic / pathology*
Thyroid Carcinoma, Anaplastic / radiotherapy
Thyroid Neoplasms / diagnostic imaging
Thyroid Neoplasms / drug therapy*
Thyroid Neoplasms / pathology*
Thyroid Neoplasms / radiotherapy
Treatment Outcome

Substances

Taxoids
Docetaxel
Carboplatin