Abstract
An efficient and high-yielding synthesis of penaresidin B is disclosed herein. The concise 8-step synthesis of azetidine aldehyde was devised by incorporating our novel strategy for ready access to 3-amino-2,3-dideoxysugars via regio- and stereoselective tandem hydroamination/glycosylation of glycal as the key step.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Aldehydes / chemical synthesis
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Aldehydes / chemistry*
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Azetidines / chemical synthesis*
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Azetidines / chemistry*
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Fatty Alcohols / chemical synthesis*
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Fatty Alcohols / chemistry
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Molecular Conformation
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Stereoisomerism
Substances
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Aldehydes
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Azetidines
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Fatty Alcohols
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penaresidin B
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azetidine