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Case Reports
. 2015 Feb 19;372(8):786-8.
doi: 10.1056/NEJMc1413931.

Viremic relapse after HIV-1 remission in a perinatally infected child

Katherine Luzuriaga  1 , Hannah Gay, Carrie Ziemniak, Keri B Sanborn, Mohan Somasundaran, Kaitlin Rainwater-Lovett, John W Mellors, Daniel Rosenbloom, Deborah Persaud
Affiliations
Case Reports

Viremic relapse after HIV-1 remission in a perinatally infected child

Katherine Luzuriaga et al. N Engl J Med. .
No abstract available

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Figures

Figure 1
Figure 1. Clinical Viral Load off Antiretroviral Treatment
*Limit of Detection <48 copies/mL for the first nine measurements, <20 copies/mL for the remaining measurements; all samples below the limit of detection were also reported out as target not detected. ZDV=zidovudine; 3TC=lamivudine LPV/r=lopinavir with boosted ritonavir; and EFV=efavirenz
Figure 2
Figure 2. Phylogenetic Analyses of Infant Rebound Plasma and Maternal Plasma Viral Sequences Amplified from Blood Collected 24 Months Prior to Rebound
Neighbor-joining tree depicts full-length gp160 env sequences. Four previously described HIV-1 clade B-infected mother/infant pairs are included in the analysis for comparison of inter-patient diversity and relatedness between mother and infant.
See this image and copyright information in PMC

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References

    1. Persaud D, Gay H, Ziemniak C, et al. Absence of detectable HIV-1 viremia after treatment cessation in an infant. N Engl J Med. 2013;369(19):1828–1835. - PMC - PubMed
    1. Tomaras GD, Haynes BF. HIV-1-specific antibody responses during acute and chronic HIV-1 infection. Curr Opin HIV AIDS. 2009;4(5):373–379. - PMC - PubMed
    1. Kishko M, Somasundaran M, Brewster F, Sullivan JL, Clapham PR, Luzuriaga K. Genotypic and functional properties of early infant HIV-1 envelopes. Retrovirology. 2011;8:67. - PMC - PubMed
    1. Wolinsky SM, Wike CM, Korber BT, et al. Selective transmission of human immunodeficiency virus type-1 variants from mothers to infants. Science. 1992;255(5048):1134–1137. - PubMed
    1. Blankson JN, Persaud D, Siliciano RF. The challenge of viral reservoirs in HIV-1 infection. Annu Rev Med. 2002;53:557–593. - PubMed