Leucocyte membrane antigens on mouse granulated metrial gland cells

J Reprod Immunol. 1989 Jul;15(3):269-79. doi: 10.1016/0165-0378(89)90017-x.


An indirect immunofluorescence technique has been used to study the expression of leucocyte membrane antigens on mouse granulated metrial gland (GMG) cells. GMG cells isolated from cultured metrial gland explants and GMG cells in cryostat sections of uterine implantation sites were examined. GMG cells were found to express both the asialo-GM1 antigen and the Thy-1 antigen. GMG cells did not express the Lyt-1, Lyt-2, Mac-1, L3T4 or IgM antigens. These results provide new evidence that GMG cells are a type of NK cell.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Antigens, Surface / analysis*
  • Antigens, Surface / immunology
  • Cells, Cultured
  • Female
  • Fluorescent Antibody Technique
  • G(M1) Ganglioside*
  • Glycosphingolipids / immunology
  • Leukocytes / immunology
  • Metrial Gland / cytology*
  • Metrial Gland / immunology
  • Mice
  • Mice, Inbred Strains
  • Pregnancy
  • Pregnancy, Animal / immunology*
  • Spleen / cytology
  • Thy-1 Antigens
  • Uterus / cytology


  • Antigens, Surface
  • Glycosphingolipids
  • Thy-1 Antigens
  • G(M1) Ganglioside
  • asialo GM1 ganglioside