[Management of hyperhidrosis]

Ann Dermatol Venereol. 2015 Apr;142(4):252-61. doi: 10.1016/j.annder.2014.11.005. Epub 2015 Feb 16.
[Article in French]

Abstract

Hyperhidrosis continues to be undertreated in our view, despite its propensity to considerably impair quality of life. We shall break down therapeutic approaches to hyperhidrosis into several steps: (a) determine the physiological causes of excess sweating; (b) establish the type of hyperhidrosis involved and screen for causes of secondary hyperhidrosis before diagnosing essential hyperhidrosis; (c) evaluate the severity of the hyperhidrosis by means of a validated scale (HDSS score), Minor's starch-iodine test or gravimetric analysis; (d) select one of the medical therapies currently available, i.e. topical therapy (antiperspirants, iontophoresis or botulinum toxin injection), systemic therapy (oxybutynin) or surgery (thoracic sympathectomy).

Keywords: Antiperspirants; Botulinum toxin; Hyperhidrose; Hyperhidrosis; Ionophorèse; Iontophoresis; Oxybutynin; Oxybutynine; Toxine botulique.

Publication types

  • Review

MeSH terms

  • Algorithms
  • Antiperspirants / therapeutic use
  • Botulinum Toxins, Type A / therapeutic use
  • Cholinergic Antagonists / therapeutic use
  • Decision Trees
  • Disease Management
  • Humans
  • Hyperhidrosis / diagnosis
  • Hyperhidrosis / physiopathology
  • Hyperhidrosis / therapy*
  • Iontophoresis
  • Severity of Illness Index
  • Staining and Labeling
  • Sweat Glands / physiopathology
  • Sympathectomy

Substances

  • Antiperspirants
  • Cholinergic Antagonists
  • Botulinum Toxins, Type A