Diagnosis and treatment of restless legs syndrome in progressive supranuclear palsy

Marcello Moccia; Marina Picillo; Roberto Erro; Roberto Allocca; Paolo Barone; Carmine Vitale

doi:10.1016/j.jns.2015.01.025

Diagnosis and treatment of restless legs syndrome in progressive supranuclear palsy

J Neurol Sci. 2015 Mar 15;350(1-2):103-4. doi: 10.1016/j.jns.2015.01.025. Epub 2015 Jan 26.

Authors

Marcello Moccia¹, Marina Picillo², Roberto Erro³, Roberto Allocca¹, Paolo Barone², Carmine Vitale⁴

Affiliations

¹ Department of Neuroscience, Reproductive Science and Odontostomatology, Federico II University, Naples, Italy.
² Center for Neurodegenerative Diseases (CEMAND), Neuroscience Section, Department of Medicine, University of Salerno, Italy.
³ Sobell Department of Motor Neuroscience and Movement Disorders, University College London, London, UK; Department of Neurological and Movement Sciences, University of Verona, Verona, Italy.
⁴ University of Naples Parthenope, Naples, Italy; IDC Hermitage-Capodimonte, Naples, Italy. Electronic address: cavit69@hotmail.com.

PMID: 25697711
DOI: 10.1016/j.jns.2015.01.025

Abstract

Restless legs syndrome (RLS) has only been recently investigated in a small cohort of progressive supranuclear palsy (PSP) patients and it has been reported to have variable prevalence (among 3.7-58%). However little is known about its management. Here, we report a case of severe RLS occurring during the course of PSP. Diagnostic issues and therapeutic approaches are discussed.

Keywords: PSP; Progressive supranuclear palsy; RLS; Restless legs syndrome; Rotigotine.

Publication types

Case Reports
Letter

MeSH terms

Dopamine Agents / therapeutic use
Humans
Male
Middle Aged
Restless Legs Syndrome / complications
Restless Legs Syndrome / diagnosis*
Restless Legs Syndrome / therapy*
Supranuclear Palsy, Progressive / complications
Supranuclear Palsy, Progressive / diagnosis*
Supranuclear Palsy, Progressive / therapy*
Treatment Outcome

Substances

Dopamine Agents