Gastroenterol Rep (Oxf). 2015 Aug;3(3):201-8. doi: 10.1093/gastro/gov004. Epub 2015 Feb 18.


Gastrin is an important hormone of the digestive system, which assists gastric acid secretion. It may be pathologically elevated in conditions such as Zollinger-Ellison syndrome, or due to common medications such as proton pump inhibitors. In this review we provide an overview of the pathophysiology and medical causes of hypergastrinemia, diagnostic testing and clinical consequences of chronic hypergastrinemia.

Keywords: carcinoid; helicobacter pylori; hypergastrinemia.

Publication types

  • Review