Weight in infancy and death from ischaemic heart disease
- PMID: 2570282
- DOI: 10.1016/s0140-6736(89)90710-1
Weight in infancy and death from ischaemic heart disease
Abstract
Environmental influences that impair growth and development in early life may be risk factors for ischaemic heart disease. To test this hypothesis, 5654 men born during 1911-30 were traced. They were born in six districts of Hertfordshire, England, and their weights in infancy were recorded. 92.4% were breast fed. Men with the lowest weights at birth and at one year had the highest death rates from ischaemic heart disease. The standardised mortality ratios fell from 111 in men who weighed 18 pounds (8.2 kg) or less at one year to 42 in those who weighed 27 pounds (12.3 kg) or more. Measures that promote prenatal and postnatal growth may reduce deaths from ischaemic heart disease. Promotion of postnatal growth may be especially important in boys who weigh below 7.5 pounds (3.4 kg) at birth.
Comment in
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Weight in infancy and death from ischaemic heart disease.Lancet. 1989 Oct 21;2(8669):984-5. Lancet. 1989. PMID: 2571896 No abstract available.
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Weight in infancy and death from ischaemic heart disease.Lancet. 1989 Dec 2;2(8675):1335. Lancet. 1989. PMID: 2574280 No abstract available.
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The effects of preterm birth and its antecedents on the cardiovascular system.Acta Obstet Gynecol Scand. 2016 Jun;95(6):652-63. doi: 10.1111/aogs.12880. Epub 2016 Mar 31. Acta Obstet Gynecol Scand. 2016. PMID: 26918772 Review.
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