Intraoperative radiotherapy of the breast for early-stage breast cancer: ready for primetime

Dennis R Holmes

doi:10.1111/tbj.12375

Intraoperative radiotherapy of the breast for early-stage breast cancer: ready for primetime

Breast J. 2015 Mar-Apr;21(2):181-4. doi: 10.1111/tbj.12375. Epub 2015 Feb 23.

Author

Dennis R Holmes¹

Affiliation

¹ Los Angeles Center for Women's Health, Los Angeles, California.

PMID: 25703933
DOI: 10.1111/tbj.12375

Abstract

The findings of the TARGIT A and ELIOT prospective, randomized controlled trials provide compelling data regarding the efficacy and safety of single fraction intraoperative radiotherapy as an alternative to standard postoperative radiotherapy in the management of early-stage breast cancer. This editorial summarizes the findings of both studies and discusses the importance of patient selection in identifying potential candidates for intraoperative radiotherapy.

Keywords: ELIOT; IORT; TARGIT; breast cancer; intraoperative radiotherapy.

Publication types

Editorial

MeSH terms

Breast Neoplasms / pathology
Breast Neoplasms / radiotherapy*
Female
Humans
Intraoperative Period
Neoplasm Staging
Patient Selection