Intraoperative radiotherapy of the breast for early-stage breast cancer: ready for primetime

Breast J. Mar-Apr 2015;21(2):181-4. doi: 10.1111/tbj.12375. Epub 2015 Feb 23.


The findings of the TARGIT A and ELIOT prospective, randomized controlled trials provide compelling data regarding the efficacy and safety of single fraction intraoperative radiotherapy as an alternative to standard postoperative radiotherapy in the management of early-stage breast cancer. This editorial summarizes the findings of both studies and discusses the importance of patient selection in identifying potential candidates for intraoperative radiotherapy.

Keywords: ELIOT; IORT; TARGIT; breast cancer; intraoperative radiotherapy.

Publication types

  • Editorial

MeSH terms

  • Breast Neoplasms / pathology
  • Breast Neoplasms / radiotherapy*
  • Female
  • Humans
  • Intraoperative Period
  • Neoplasm Staging
  • Patient Selection