Development of effective connectivity in the core network for face perception

Hum Brain Mapp. 2015 Jun;36(6):2161-73. doi: 10.1002/hbm.22762. Epub 2015 Feb 19.


This study measured effective connectivity within the core face network in young children using a paediatric magnetoencephalograph (MEG). Dynamic casual modeling (DCM) of brain responses was performed in a group of adults (N = 14) and a group of young children aged from 3 to 6 years (N = 15). Three candidate DCM models were tested, and the fits of the MEG data to the three models were compared at both individual and group levels. The results show that the connectivity structure of the core face network differs significantly between adults and children. Further, the relative strengths of face network connections were differentially modulated by experimental conditions in the two groups. These results support the interpretation that the core face network undergoes significant structural configuration and functional specialization between four years of age and adulthood.

Keywords: childhood; cortical network; dynamic causal modeling; face processing; magnetoencephalography.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Bayes Theorem
  • Brain / growth & development*
  • Brain / physiology*
  • Brain Mapping / methods
  • Child
  • Child, Preschool
  • Evoked Potentials, Visual / physiology
  • Facial Recognition / physiology*
  • Female
  • Humans
  • Magnetoencephalography / methods
  • Male
  • Neural Pathways / growth & development
  • Neural Pathways / physiology
  • Photic Stimulation
  • Signal Processing, Computer-Assisted