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. 2015 Apr:102:61-6.
doi: 10.1016/j.fitote.2015.02.005. Epub 2015 Feb 20.

New triquinane and gymnomitrane sesquiterpenes from fermentation of the basidiomycete Antrodiella albocinnamomea

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New triquinane and gymnomitrane sesquiterpenes from fermentation of the basidiomycete Antrodiella albocinnamomea

Zi-Ming Chen et al. Fitoterapia. 2015 Apr.

Abstract

Five new triquinane-type sesquiterpenes, antrodins A-E (1-5) and a new gymnomitrane sesquiterpene, antrodin F (6), together with three known compounds 7-9 were isolated from fermentation of Antrodiella albocinnamomea. Their structures were elucidated through extensive spectroscopic methods including 2D NMR and HRMS analyses. The absolute configurations of 1 and 6 were determined using single-crystal X-ray diffraction analyses. The isolated compounds were investigated for their cytotoxicities against five human cancer cell lines.

Keywords: Antrodiella albocinnamomea; Gymnomitrane; Triquinane.

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