New triquinane and gymnomitrane sesquiterpenes from fermentation of the basidiomycete Antrodiella albocinnamomea
- PMID: 25704368
- DOI: 10.1016/j.fitote.2015.02.005
New triquinane and gymnomitrane sesquiterpenes from fermentation of the basidiomycete Antrodiella albocinnamomea
Abstract
Five new triquinane-type sesquiterpenes, antrodins A-E (1-5) and a new gymnomitrane sesquiterpene, antrodin F (6), together with three known compounds 7-9 were isolated from fermentation of Antrodiella albocinnamomea. Their structures were elucidated through extensive spectroscopic methods including 2D NMR and HRMS analyses. The absolute configurations of 1 and 6 were determined using single-crystal X-ray diffraction analyses. The isolated compounds were investigated for their cytotoxicities against five human cancer cell lines.
Keywords: Antrodiella albocinnamomea; Gymnomitrane; Triquinane.
Copyright © 2015 Elsevier B.V. All rights reserved.
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