Complex investigation of solar, geophysical and meteorological factors as well as lunar cycle-phases effects on the indices of cardiohemodynamics, emotional state and the CNS functional state was carried out in 12 males 19-38 years old living in the Arctic region (Apatity, 67°57' N, 33°39' E). The observation period was characterized by flares of M1-M2-class as well as geomagnetic storms of G1-G3 class. Adaptive modulatory effect of environmental factors was shown on the autonomic regulatory systems, as well as a strongviolation action of geomagnetic storms and solar chromosphere flares were revealed on the human functional state. Multiple regression method allowed us to obtain the dominant environmental factors by magnitude of their action on functional parameters, and to estimate the combined effect of these factors. The coefficient of determination in the most cases did not exceed 0.5, but in a certain subjects reached 0.7-0.8 on some indicators. Data show the selective nature of the multiple effects of environmental factors on indicators of functional and emotional states at various persons. Each of examined subjects living in the high latitude extreme conditions reacts on permanent climatic-geographic and cosmophysical factors variation, however both a character and magnitude of reactions were dependent on personal susceptibility to isolated and combined actions of these factors.