Hepatitis E virus genotype-3 (HEV3) infection can cause chronic hepatitis in immunosuppressed patients and induce extra-hepatic manifestations, such as neurological symptoms, kidney injuries, and immune-mediated thrombocytopenia. Very few cases of HEV-induced kidney manifestations have been reported. Herein, we report, for the first time, a case of de novo membranoproliferative glomerulonephritis that occurred in a kidney transplant patient who developed a chronic HEV3 infection, which was successfully treated with ribavirin.
Keywords: de novo glomerulopathy; hepatitis E virus; kidney transplantation; membranoproliferative glomerulonephritis; ribavirin.
© 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.