Humanitarian access to unapproved interventions in public health emergencies of international concern

PLoS Med. 2015 Feb 24;12(2):e1001793. doi: 10.1371/journal.pmed.1001793. eCollection 2015 Feb.


Jerome Singh considers how regulatory mechanisms can allow access to experimental interventions in humanitarian emergencies such as the Ebola epidemic.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Altruism*
  • Ebolavirus
  • Emergencies*
  • Epidemics
  • Global Health*
  • Hemorrhagic Fever, Ebola / epidemiology
  • Hemorrhagic Fever, Ebola / therapy*
  • Hemorrhagic Fever, Ebola / virology
  • Humans
  • International Cooperation*
  • Public Health*
  • Relief Work
  • Therapies, Investigational*

Grant support

The author is supported by the Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa, which forms part of the Comprehensive International Program on AIDS, funded by the US National Institute of Allergy and Infectious Diseases. The author is also supported by the HIV Prevention Trial Network. No specific funding was received for writing this article. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. The views of the writer do not necessarily reflect the views of his funders or employers.