Urethral condylomas in men: experience in 123 patients without previous treatment

Int J STD AIDS. 2016 Jan;27(1):39-43. doi: 10.1177/0956462415574627. Epub 2015 Feb 22.


The most common sexually transmitted infection (STI) is infection by human papillomavirus. There are more than 100 types of human papillomavirus, and over 30 of them involve the genital area. Urethral involvement is uncommon and usually limited to the distal 3 cm of the meatus. There are various treatments for urethral condylomas; as a rule, they are limited by a difficult approach, by recurrences, and by potential complications, the most significant of which is urethral stenosis. The purpose of the treatments is to remove the warts and induce lesion-free periods. Such treatments do not eliminate the infection nor do they prevent continued transmission of the virus. We retrospectively evaluated 123 patients diagnosed and treated for condylomas in the genital area at our Institution between April 2009 and April 2012. The patients' mean age was 28.7 years (range 19-51). Of the 123 patients included, 48 (39%) had a history of previous STIs, most frequently gonococcal urethritis. Three of them had a urethral malformation in the form of hypospadias, and another three reported a previous urologic manipulation (catheterisation). Meatal/urethral condylomas are rare, cryotherapy is simple, easy to apply, and has a very low risk of complications in patients with externally accessible warts.

Keywords: 5% fluorouracil gel; HPV; Meatal/urethral condyloma; Sexually transmitted infection; conservative treatment; cryotherapy; genital warts; human papillomavirus; men; treatment.

Publication types

  • Evaluation Study

MeSH terms

  • Adult
  • Condylomata Acuminata / therapy*
  • Condylomata Acuminata / virology
  • Cryotherapy*
  • Humans
  • Male
  • Middle Aged
  • Papillomaviridae
  • Papillomavirus Infections / therapy*
  • Papillomavirus Infections / virology
  • Retrospective Studies
  • Treatment Outcome
  • Urethral Diseases / therapy
  • Urethral Diseases / virology*