Association of painful peripheral neuropathy in AIDS with cytomegalovirus infection

G N Fuller; J M Jacobs; R J Guiloff

doi:10.1016/s0140-6736(89)90952-5

Association of painful peripheral neuropathy in AIDS with cytomegalovirus infection

Lancet. 1989 Oct 21;2(8669):937-41. doi: 10.1016/s0140-6736(89)90952-5.

Authors

G N Fuller¹, J M Jacobs, R J Guiloff

Affiliation

¹ Department of Neurology, Charing Cross and Westiminster Medical School, London.

PMID: 2571861
DOI: 10.1016/s0140-6736(89)90952-5

Abstract

12 AIDS patients with a clinically, electrophysiologically, and pathologically homogeneous painful peripheral neuropathy had a significantly higher rate of any or active clinical cytomegalovirus (CMV) infection than did a group of 30 AIDS controls. In 9 patients this syndrome began in close temporal association with clinical infection with CMV. Painful peripheral neuropathy in AIDS may be caused by a CMV dorsal root ganglionitis.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Acquired Immunodeficiency Syndrome / complications*
Adult
Cytomegalovirus Infections / complications*
Cytomegalovirus Infections / etiology
Electrophysiology
Homosexuality
Humans
Male
Pain / etiology*
Peripheral Nervous System Diseases / etiology
Peripheral Nervous System Diseases / pathology
Peripheral Nervous System Diseases / physiopathology
Spinal Nerves*
Sural Nerve*
Time Factors