Urinary Retention Due to Severe Pseudocystic Mucoid Degeneration of the Prostatic Matrix: A Rare Urologic Manifestation of Cystic Fibrosis

Urol Int. 2015;95(4):486-8. doi: 10.1159/000368911. Epub 2015 Feb 20.


Cystic fibrosis (CF) is an autosomal recessive genetic disease, which is characterized by the production of thick mucus in exocrine glands. The main cause for morbidity and mortality in CF patients is respiratory failure. The gastrointestinal system is also commonly affected. Urologic manifestations of CF include infertility and azoospermia, nephrolithiasis, and stress urinary incontinence. In this report, we describe a 33-year-old male, who presented with recurrent urinary retention due to prostatic enlargement despite his young age. After transurethral resection, the voiding problems resolved. Histopathological examination, however, revealed a severe pseudocystic mucoid degeneration of the prostatic matrix as a cause of his subvesical obstruction. Although these structural changes are most probably due to his underlying disease, detailed histologic features have not been described in the literature.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Cystic Fibrosis / complications*
  • Cystic Fibrosis / diagnosis
  • Diagnosis, Differential
  • Endosonography
  • Follow-Up Studies
  • Humans
  • Male
  • Prostate / diagnostic imaging
  • Prostate / pathology*
  • Prostatectomy
  • Prostatic Hyperplasia / complications*
  • Prostatic Hyperplasia / diagnosis
  • Prostatic Hyperplasia / surgery
  • Rectum
  • Severity of Illness Index
  • Urinary Retention / diagnosis
  • Urinary Retention / etiology*
  • Urinary Retention / physiopathology
  • Urination / physiology*