Traumatic brain injury in the elderly: morbidity and mortality trends and risk factors

J Surg Res. 2015 May 1;195(1):1-9. doi: 10.1016/j.jss.2015.01.017. Epub 2015 Jan 15.


An estimated 1.7 million people sustain a traumatic brain injury (TBI) annually in the United States. We sought to examine factors contributing to mortality among TBI patients aged ≥65 y in the United States. TBI data from the Nationwide Inpatient Sample were combined from 2000-2010. Patients were stratified by age, sex, mechanism of injury, payer status, comorbidity, injury severity, and other factors. Odds of death were explored using an adjusted multivariable logistic regression. A total of 950,132 TBI-related hospitalizations and 107,666 TBI-related deaths occurred among adults aged ≥65 y from 2000-2010. The most common mechanism of injury was falling, and falls were more common among the oldest age groups. Logistic regression analysis showed highest odds of death among male patients, those whose mechanism of injury was motor vehicle related, patients with three or more comorbidities, and patients who were designated as self-paying.

Keywords: Morbidity; Mortality; Older adult; Risk factors; TBI.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Aged, 80 and over
  • Brain Injuries / mortality*
  • Female
  • Hospital Mortality / trends
  • Hospitalization / statistics & numerical data
  • Humans
  • Male
  • Retrospective Studies
  • Risk Factors
  • United States / epidemiology