Chia induces clinically discrete weight loss and improves lipid profile only in altered previous values

Nutr Hosp. 2014 Dec 14;31(3):1176-82. doi: 10.3305/nh.2015.31.3.8242.


Introduction: chia (Salvia hispanica L.) has an elevated concentration of dietary fiber, it has been used to weight loss and enhance blood glucose and lipid profile. However, data in human are still scarce or do not exist, according to the analyzed variable.

Aim: to evaluate the effect of chia supplementation in body composition, lipid profile and blood glucose in overweight or obese individuals.

Methods: men and women were randomly allocated in groups that ingested 35 g of chia flour/day (CHIA; n=19; 48.8±1.8 years) or placebo (PLA; n=7; 51.4±3.1 years) for 12 weeks. Body composition and food intake were evaluated in each four weeks. Lipid profile and blood glucose were measured in the beginning and in the end of the study.

Results: Chia induced significant intragroup reduction in body weight (-1.1±0.4 kg; p<0.05), with a greater reduction among obese than overweighed individuals (-1.6±0.4 kg; p<0.00), but without difference when compared to PLA. Waist circumference reduced 1.9±0.6 cm in CHIA group (p <0.05), but only intragroup. It was observed a reduction in total cholesterol (p=0.04) and VLDL-c (p=0.03), and an increase in HDL-c (p=0.01) but only in the groups that ingested chia flour and presented abnormal initial values. Triglycerides, blood glucose and LDL-C showed no changes for either group.

Conclusion: consumption of chia for 12 weeks promotes significant but discrete reduction in weight and waist circumference, and enhances lipid profile dependent of initial values.

Introducción: Debido al alto contenido de fibra dietética, la chía (Salvia hispánica L.) han sido propuesta para la pérdida de peso y mejora del perfil lipídico y glucémico. Pero los datos en humanos son escasos o inexistentes, en función de la variable analizada. Objetivo: Evaluar el efecto de la suplementación con harina de chía en la composición corporal, perfil lipídico y glucémico de individuos con sobrepeso y obesidad. Métodos: hombres y mujeres fueron asignados aleatoriamente en grupos que consumieron 35 g / día de chía (CHIA; n = 19; 48.8 ± 1.8 años) o placebo (PLA; n = 7; 51.4 ± 3.1 años) durante 12 semanas. La composición corporal y el consumo de alimentos fueron evaluados la cada cuatro semanas de intervención. Perfil lipídico y los niveles de glucosa se midieron al principio y al final del estudio. Resultados: La chía promovió reducción significativa en el peso corporal (-1.1kg; p.

Publication types

  • Comparative Study
  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Aged
  • Blood Glucose / analysis
  • Body Composition
  • Cholesterol / blood
  • Diet, Reducing*
  • Dietary Fiber / therapeutic use
  • Dietary Supplements*
  • Double-Blind Method
  • Dyslipidemias / blood
  • Dyslipidemias / diet therapy*
  • Eating
  • Female
  • Humans
  • Lipids / blood*
  • Male
  • Middle Aged
  • Obesity / blood
  • Obesity / diet therapy
  • Overweight / blood
  • Overweight / diet therapy*
  • Phytotherapy*
  • Salvia*
  • Waist Circumference


  • Blood Glucose
  • Dietary Fiber
  • Lipids
  • Cholesterol