[Study of serum albumin and BMI as nutritional markers in hemodialysis patients]

Nutr Hosp. 2014 Oct 3;31(3):1317-22. doi: 10.3305/nh.2015.31.3.8084.
[Article in Spanish]

Abstract

Background: Protein calorie malnutrition as well as systemic inflammation and metabolic disorders are common among patients with chronic renal failure undergoing renal replacement therapy (haemodialysis), which contributes to its morbidity and mortality.

Aims: The aims of this work was to evaluate the nutritional status of patients in a hemodialysis treatment through the assessment of biochemical parameters nutritional as albumin, and anthropometric parameters of body mass index during ten years of follow up.

Methods: In this work has been followed 90 patients of both sexes with chronic kidney disease who were treated with hemodialysis regularly on our unit for ten years. All patients were conducted quarterly measurements of plasma albumin (Alb), and other biochemical determinations, and anthropometric measurements of height, weight and body mass index calculated by the formula weight/height², grouped n BMI < 23 kg/m² and albumin levels <3.8 g/dl according to the consensus of the panel of experts of the International Society for renal Nutrition and metabolism.

Results: During the 10 years all patients showed a significant decline in the biochemical parameters and the albumin, change in BMI does not presented significant changes in relation to malnutrition.

Conclusions: Malnutrition in patients on dialysis is a fact patent, BMI does not correspond with the biochemical parameters were observed, for what nutritional impairment in these patients is mainly expressed by serum albumin.

Introducción: La malnutrición proteíco calorica asi como la inflamación sistémica y metabólica son trastornos frecuentes entre los pacientes con insuficiencia renal crónica sometidos a tratamiento renal sustitutivo (Hemodiálisis), lo que contribuye a su morbilidad y mortalidad. Objetivos: El objetivo de este trabajo fue evaluar el estado nutricional de los pacientes de una unidad de hemodiálisis mediante la valoración de parámetros bioquímicos nutricionales como la albúmina, y parámetros antropométricos de índice de masa corporal durante diez años de seguimiento. Métodos: En este trabajo se ha seguido a 90 pacientes de ambos sexos con insuficiencia renal crónica que fueron tratados con hemodiálisis periódicamente en nuestra unidad durante diez años. A todos los pacientes se le realizaron mediciones trimestrales de albúmina plasmática (Alb), y otras determinaciones bioquimicas, y se les efectuaron mediciones antropométricas de peso, altura e índice de masa corporal calculado mediante la formula peso/talla², agrupada enIMC < 23 kg/m2 y niveles de albumina.

Publication types

  • English Abstract

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Biomarkers
  • Body Mass Index*
  • C-Reactive Protein / analysis
  • Disease Progression
  • Female
  • Follow-Up Studies
  • Homocysteine / blood
  • Humans
  • Kaplan-Meier Estimate
  • Lipids / blood
  • Male
  • Malnutrition / diagnosis*
  • Malnutrition / etiology
  • Middle Aged
  • Nutritional Status*
  • Protein-Energy Malnutrition / diagnosis
  • Protein-Energy Malnutrition / etiology
  • Renal Dialysis* / adverse effects
  • Renal Insufficiency, Chronic / complications
  • Renal Insufficiency, Chronic / therapy*
  • Sampling Studies
  • Serum Albumin / analysis*

Substances

  • Biomarkers
  • Lipids
  • Serum Albumin
  • Homocysteine
  • C-Reactive Protein